Shaik Kareemulla*1, Dr.
Pankaj Kumar Sharma2, Dr. Khaja Pasha3
Research Scholar, Jaipur National University (JNU), Rajasthan
& Senior Assistant Director (Pharmacy), Jaipur National University (JNU), Rajasthan
3 Professor, Dept. of Pharmaceutical Analysis,
Jawahalal Nehru Technological University (JNTU), Hyderabad
Antibiotics are the most
commonly prescribed drugs in hospitals. In developed countries, around 30% of
the hospitalized patients are treated with antibiotics. Rational uses of drugs have attained
more significance in present days in terms of medical, socio economical and
legal aspects . Pharmacists
play a vital role in promoting the rational use of medicines. Medicines
(drugs) cannot be used rationally unless all health care professionals involved
in the pharmaceutical supply chain has access to know the complete information
therapeutic indications of the drugs This
study was carried out to collect patient’s relevant demographic information which
includes Age, Sex, Occupation, Date of admission, Date of discharge, History of
present illness, past medical history, Diagnosis and prescription drugs .
1) The aim of the research is to study and to determine the prescribing
patterns of antibiotics and use of antibiotic (Rational / Irrational) in a
tertiary care hospital along with its beneficial and adverse outcomes. 2)
Intervene strategies from pharmacist perspective to promote rational use of
antibiotics to improve therapeutic outcomes in patients thereby improving
quality of life (QOL) of patients . The study was carried at Shadan Institute of Medical
Sciences, Shadan Hospital, Hyderabad. Antibiotics are prescribed based on
symptoms and laboratory investigations. Antibiotics are indicated for the
treatment of bacteriologically proven infections and non-bacteriologically
proven infections. It is a single centered,
prospective observational study. Subjects of both genders who indicated with
antibiotic therapy are taken into consideration and patients who had co morbid
pathological conditions also included. Pediatrics, pregnant women and surgical
cases were excluded from the study .175
patients were collected; 75 were male and 100 were female. Total numbers of
antibiotics prescribed are 260. Median duration of hospitalization was 5 days.
The most common prescribed antibiotics were Ceftriaxone, Ciprofloxacin, Azithromycin,
Amoxicillin+Clavulanic acid, Amikacin & Doxycycline. On assessing
the results of study, it was found that prescribed 260 antibiotics accounted
for 100%, ceftriaxone indicated was 35% followed by ciprofloxacin was 10 % and
azithromycin was 6%. Irrational prescriptions
becoming a serious problem in the General medicine department. For the
achievement of Rational use of antibiotic to treat infections caused by
microorganisms, selection the appropriate antibiotic partly depends on symptoms
suffered by the patients. Awareness programs should be launched and seminars
should be conducted so as to minimize problems which are common at ward level .
News Letters and Drug bulletins about the rational use of antibiotics should be
released periodically. Cost effective prescription should be encouraged. Formulation of a policy for hospital antibiotic use
and educational programs especially for junior doctors also required.
Keywords: Antibiotics, Drug utilization, General Medicine
ward, Rational prescription, Quality of life, Cost effective prescription.