Formulation and Evaluation of Aloe Vera Gel and Film From Fresh Pulp of the Leaves of Aloe Barbadensis
Tirupati Rasala*, Shivani Dani, Shekhar Waikar, Abhay Ittadwar.
Gurunanak College of Pharmacy, Dixit Nagar, Behind CP Foundary, Nari, Nagpur-440026
The historians have recorded many applications of aloe species both in the medical field as well as in cosmetics. It is used to heal burns, to prevent blisters for the treatment of wounds and in various kinds of damaged skin. Burns are serious traumas related to skin damage, causing extreme pain and natural drugs such as Aloe vera is beneficial in formulations for wound healing. The aim of this work is to develop and evaluate polymeric films containing Aloe Vera crude extracts to smoothen and treat minor wounds caused by burns. Polymeric films containing different quantities of HPMC and polyvinyl alcohol (PVA) were characterized for their mechanical properties. The polymeric films, which were formulated, were found to be thin, flexible, resistant, and suitable for application on damaged skin, such as in burns & wounds. The formulated gel was evaluated for evaluations parameters were thickness, tensile strength and water vapour permeability. general appearance, homogeneity, pH, spreadability test, washed test and skin irritation test. Film
Keywords: Aloe Vera, Gel and Film.