Bars (Vitiligo) is an acquired depigmentation of the skin, characterized by well-circumscribed, ivory or chalky white macules which are flush to the skin surface.These patches look ugly, especially in persons with dark complexion. It affects 1% of the population worldwide. Both sexes are affected equally. It is a disease of antiquity. The renowned Unani physicians like Razi, Majoosi, Rabbn Tabri and Ibne Sina all have mentioned this disease in their books.  An observational non randomised study was conducted on thirty patients. Sheetraj Hindi (Plumbago zeylanicum) and Neela thotha (copper Sulphate) was powdered mixed and applied locally for three months. The overall response was found encouraging, achieved cured in 6.37%, very good response in 7.00%, good response 26.33%, fair response in 25%, poor response in 16.47%, slow response in 15.5%, and no response in 3.33% of patients in 3 months duration.