The effect of Nigerian dietary vegetable mixtures composed of Vernonia amygdalina, Ocimum gratissimum, Gongronema latifolium, Solanum melongena, Phyllanthus amarus, and Piper nigrumas acclaimed as potent anti-hyperglycaemic agents were evaluated in accordance with local finished medicine products and practices in alloxan-induced diabetic guinea pigs. Blood glucose level analysis was used as diabetic indices. Taken together, the results of the present study, suggests that the strong cooperative additive/synergistic effects of the dietary vegetable mixtures (50/50/50) significantly (p