After the Human Immunodeficiency Virus (HIV) from a single infectious agent the Tuberculosis (TB) is a second leading cause of death 1. The highest absolute number of TB cases occurred in Twenty-two high-burden countries (HBCs) account for 81% of all TB around the world. Currently about one-third population of the world are carriers of TB. In each year an average 9 million people are infected with active TB disease. World Health Organization (WHO) declares the TB in 1993, a global health emergency by. In 1996, approximately 3 million persons die from the TB 2. In 2008, 9.2 million new cases and 1.7 million deaths from TB (of which 0.7 million cases with Human immunodeficiency virus (HIV) and 0.2 million deaths were in HIV positive patient) were recorded 3. In 2008, worldwide approximately 440,000 cases of MDR-TB were reported 4. While, in 2009, 9.4 million new cases of TB along with 1.7 million deaths were occurred. In 2010 an estimated 12 million people were living with active TB.