American Journal of Pharmacy and Health Research

AJPHR

2321-3647

AJPHR204010

Ethanol extract of Ricinus Communis increased Reproductive Hormones in Female Albino rats

Onuka

Agbai Emmanuel

Arthur

Prof. Nwafor

Department of Human Physiology, Faculty of Basic Medical Sciences, College of Medicine, Madonna University, PMB 48 Elele, Rivers State, Nigeria. Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, PMB 5323, Choba, Port Harcourt, Rivers State, Nigeria.

04 01 2014

2 4

The effect of 100, 300 and 500 mg/kg of ethanol extract of ricinus communis extract on reproductive hormone: estrogen, progesterone, LH and FSH was investigated using virgin female albino wistar rats. The results showed that at lower doses ricinus communis extract caused a decrease in estrogen, progesterone and LH levels at P < 0.05, but at high dose of 500mg/kg it caused an increase in estrogen, progesterone levels at P < 0.05. The extract did not have significant effect on FSH at P > 0.05. Data suggested that the extract increased the hormones in a dose-dependent fashion. Keywords. Ricinus communis. progesterone. estrogen. luteinizing hormone. follicle stimulating hormone.

Ricinus communis. progesterone. estrogen. luteinizing hormone. follicle stimulating hormone.