In the present study ethanol and aqueous extracts of the whole plant of Merremia emarginata Burm. F were investigated for their anthelmintic activity against Ecinia foeitida and Pheretima posthuma. Four concentrations (100, 150, 200, 250 mg/ml) of each extract were subjected for evaluation. The study is mainly concerned with the determination of time of paralysis and time of death of the parasites. The gradual increase in the dose showed a gradual increase in the anthelmintic activity. The ethanolic extract of the whole plant showed a significant anthelmintic activity at highest concentration of 250 mg/ml.