Bars (Vitiligo) is the oldest and commonest skin disorders affecting approximately 0.1% to 2% of the world’s population, and its prevalence is varying from 0.46% to 8.8 % in India. The disease shows no regard to the cultural, ethnic or socioeconomic background of the affected population. The cosmetic impact of this disease is huge and psychological impact is devastating, particularly in coloured races. In Unani system of medicine Majoon Atrilaal and local application of Sheetraj and Nila Tootiya have been used for the management of Bars since centuries, but the efficacy has yet to be proven on scientific parameters. Observational single blinded study was carried out on 20 clinically diagnosed patients of Bars. They were treated with 10 gm of Majoon Atrilaal, orally twice daily and Sheetraj with Nila Tootiya applied locally once in the morning, for a period of three months. The subjective parameter (hypo pigmented patches) and objective parameter (VASI) were statistically analyzed by applying Student ‘t’ test (two tailed dependent) and paired proportion test. VASI (Vitiligo Area Scoring Index) showed significant difference P