The genus Salvia, composed of more than 900 species worldwide distributed, is well known for its various uses, including therapeutic ones. Many species within the genus exhibit activities such as antioxidant, anti-inflammatory, antimicrobial etc. The chemical composition of these species includes polyphenols, flavonoids, terpenes, which induce such activities. The present study compares the polyphenolcarboxilic acids and flavonoids content of 3 species of Salvia present in Ukrainian flora, including S. patens L. and S. verticillata L. Using a HPLC method, polyphenolcarboxilic acids and flavonoid compounds were determined in S. officinalis L., S. patens L. and S. verticillata L.