In developing countries like India, majority of healthcare is borne to private sector, resulting that most of the people levy on local /available unrecognized medical practitioners. The RMP’s are very popular in the rural areas and urban slums because they are the primary contact in the medical emergencies that leads to some drug related errors, adverse effects and interactions. The quality of life in developing countries can be improved by enhancing the standards of medical treatment at all levels of the health care delivery system. This can be achieved through interventions, continuous medical education programs, effective implementation of therapeutic strategies. Our investigation is to study about the impact of RMP’s treatment and to ensure the drug safety by clinical pharmacy services in rural India.