This study describes the demographic status of HIV-infected people in Pakistan. The major risks factors involve in the spread HIV infection among the population of Pakistan are discussed. The overall prevalence of HIV has been observed to be getting higher as compared to the prevalence of early years. Use of population-based surveillance data provided a glimpse of need to spread the knowledge of HIV safety programs among each and every individual of Pakistan. Our findings emphasize the importance of targeting HIV testing and prevention efforts to populations at risk of HIV.