ABSTRACTWounds can cause painful lengthy hospital stay, multiple stages of surgeries, and enormous financial burden. During the last decade, various new dressing materials developed, like calcium alginate, hydro- colloid membranes and fine mesh gauze. These have disadvantage in that they become permeable to bacteria. Biological dressings like collagen on other hand, create the most physiological interface between the wound surface and environment, and impermeable to bacteria. Biological dressing’s collagen granule dressing has advantage over conventional dressing in terms of, non-immunogenic, non-pyrogenic, being natural, easy application and decreased days of healing. Keywords: Collagen dressing, chronic Wounds, Wound Healing, Wound History, wound dressing