ABSTRACTTuberculosis is a bacterial infectious disease caused by Mycobacterium tuberculosis. It is highly infectious and opportunistic disease. The synthetic drugs for anti-tuberculosis effect have been prescribed for symptomatic control of disease but produce much adverse effect. Naturally obtaining medicinal plants are incomparable resources of Siddha. From thousands of years, medicinal plants provide a great hope to curing diseases. This review spotlights the effort on anti-tubercular plants, which are various source of literature. This paper provides the plant description, chemical constituents, evidence based pharmacological activity. This will motivate and provide a way for further researches on medicinal plants, possess potent anti- tuberculosis activity. Keywords: Tuberculosis, Anti-tubercular activity, Medicinal plants, Siddha.