American Journal of Pharmacy and Health Research AJPHR 2321-3647 10.46624/ajphr.2018.v6.i4.003 AJPHR604003 Effect of Altitude (2500 M) on The Pharmacokinetics of Diclofenac Sodium and Cefadroxil After Oral Administration To Human Volunteers Fergany.A. Mohammed Fergany.A. Mohammed Hussein Mostafa.A. Faculty of Pharmacy, Assiut University, Assiut-Egypt 04 01 2018 6 4

ABSTRACTThis paper reports, for the first time, the data on the pharmacokinetic characteristics of diclofenac sodium and cefadroxil at Albaha, 2500 M altitude (ALT) , KSA. Therefore, the objective of this study was to compare the plasma concentrations and  pharmacokinetic parameters of diclofenac sodium (Voltaren

 altitude- ALT- SEA- diclofenac sodium- cefadroxil- fully validated HPLC- drug concentrations- pharmacokinetic parameters- statistical analysis - significant differences- dosage regimen adjustment -avoid drug s toxicity