ABSTRACTAlcohol abuse is one of major and increasingly attributable risk factor for mortality and morbidity worldwide. The underlying purpose of this review is to promote awareness and significance in relation to the effects of alcohol on various body systems especially on cardiovascular system, liver, adipose tissue, skeletal muscle, brain, water and electrolyte metabolism and endocrine system. Alcohol when used above the normal range can results in harmful consequences on different biological organs. Average volumes consumed and patterns and frequency of drinking are three dimensions of alcohol consumption that need to be considered in efforts to reduce the burden of alcohol-related harmful effects. To reduce such harmful effects, national policies need to be developed to keep track of alcohol consumption and its consequences, and to raise awareness amongst the public. It is up to both public and concerned governments to encourage debate and formulate effective public health oriented policies and measures in order to minimize the harm caused by alcohol. Keywords: Alcohol, consumption, harmful effects, awareness