ABSTRACTSexual dysfunction is defined as any discomfort experienced by an individual or a couple during any stage of a normal sexual activity.  According to ICD-10 sexual dysfunction is a condition in which an individual or couple is unable to perform sexual intercourse as both would wish. Atherosclerosis of the arteries supplying genital tissue which elevate sexual function. Typical antipsychotic induce relatively high chances of developing sexual dysfunction in comparison to atypical antipsychotics. Keywords : Sexual dysfunction, Antipsychotics, Sexual intercource, ICD-10.