ABSTRACTBryophyllum pinnatum is one of the important and most commonly used plant belongs to the family crassularaceae. This plant is mainly used as a tropical medicinal plant in India, America and other countries. The presence of various chemical constituents in this plant can be used as a medicine for various diseases. The important chemical constituents present in the plant include alkaloids, triterpenes, flavonoids, lipids, glycosides, phenols, bufadienolides, and organic acids. Due to the presence of these chemical constituents Bryophyllum pinnatum shows various pharmacological activities like, nephroprotective, antioxidant, analgesic, anti-diabetic, antimicrobial, anticonvulsant antipyretic, and neuropharmacological activity. This review covers various pharmacological activities of the plant Bryophyllum pinnatum. Keywords: Bryophyllum pinnatum, Plant, glycosides, leaves.