ABSTRACTNow a days the synthetic and novel drugs are the major source of curing any type of disease, although these chemically synthesized drugs are harmful hazardous and shows toxic effect on the human body, this research formulation is a Polyherbal product (expectorant) which is useful and effective to treat the acute as well as chronic cough mainly chronic cough in patients of all ages. The prolonged chronic cough which last for several months or even years (in some patients) so to treat this “polyherbal anti-tussive syrup” is best mode, this syrup consist of some prominent and effective naturally occurring drugs or medicinal plants like, cinnamon, clove, black paper, Tulsi , honey (as base), and menthol (as cooling agent expectorants). This particulate combination of drugs is very effective for the treatment of cough, although this syrup can also be used for the treatment of the common cold respiratory disorders or nasal problems.        Keywords: Anti-tussive, Medicinal Plants, Polyherbal Formulation, Expectorants, Cough Syrup