ABSTRACTObesity is an independent risk factor for cardiovascular disease (CVD). Obesity is associated with an increased risk of morbidity and mortality as well as reduced life expectancy. The last two decades of the previous century have witnessed dramatic increase in health care costs due to obesity and related issues among children and adolescents. The emerging epidemics of obesity, CVD and diabetes form the crux of this phenomenal change. Among these entities, obesity has become a colossal epidemic causing serious public health concern and contributes to 2.6 million deaths worldwide every yearr. The open label randomized clinical trial on 60 diagnosed patients of obesity, aged between 20-50 years. An Unani formulation -compound of Luk Maghsul (Tachardia Laccca),Ajwain Desi (Trachyspermum ammi) & Zeera Siyah (Carum carvi) is given for 90 days. The “P” value of each intervention groups on all parameters is P= 0.001. Keywords: Samane Mufrit; Luk Mughsul; Ajwain Desi; Lac; Zeera Siyah.