Validated UV-Spectrophotometric Method for the Assay of Voriconazole in Pure and Formulations

Q: Who are the authors of this article and where was it published?

B.V.Sreenivasulu, C.Rambabu. Published in American Journal of Pharmacy and Health Research, Vol. 2, No. 12, (2014).

Q: Is the full text of this article freely available?

Yes. This article is published open access under CC BY 4.0. The full text and PDF can be downloaded free of charge.

Q: What are the key topics covered in this article?

Voriconazole, UV-Spectrophotometry, Dosage forms..

B.V.Sreenivasulu; C.Rambabu

Published

Validated UV-Spectrophotometric Method for the Assay of Voriconazole in Pure and Formulations

B.V.Sreenivasulu

,

C.Rambabu

Published in December 2014 Issue 12 (Vol. 2, Issue 12, 2014)

Validated UV-Spectrophotometric Method for the Assay of Voriconazole in Pure and Formulations - Issue cover

Keywords

Voriconazole UV-Spectrophotometry Dosage forms.

Abstract

A simple, accurate, cost effective and reproducible UV-Spectrophotometric method has been developed and validated for the estimation of voriconazole in pure and dosage forms. The present UV-spectrophotometric method is based on measurement of absorption at maximum wavelength of 256nm. The Beer’s law of this method was obeyed in the concentration range of 5-30μg/ml with the linear equation of Y = 0.0218x - 0.0029 and correlation coefficient of 0.9996. The percentage recovery of voriconazole ranged from (99.96) in pharmaceutical dosage forms.

Authors (2)

B.V.Sreenivasulu

Department of Biochemistry, Ac...Department of Biochemistry, Acharya Nagarjuna Univ...Department of Biochemistry, Acharya Nagarjuna University,Guntur,AP,Ind...Department of Biochemistry, Acharya Nagarjuna University,Guntur,AP,India.

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C.Rambabu

Department of Chemistry, Achar...Department of Chemistry, Acharya Nagarjuna Univers...Department of Chemistry, Acharya Nagarjuna University,Guntur,AP,India.Department of Chemistry, Acharya Nagarjuna University,Guntur,AP,India.

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Article Information

Published in:

December 2014 Issue 12 (Vol. 2, Issue 12, 2014)

Article ID:

AJPHR212013

Paper ID:

AJPHR-01-000270

Pages:

1-7

Published Date:

2014-12-01

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Citation Format

B.V.Sreenivasulu, & C.Rambabu (2014). Validated UV-Spectrophotometric Method for the Assay of Voriconazole in Pure and Formulations. American Journal of Pharmacy and Health Research, 2(12), 1-7. https://ajphr.com/articles/AJPHR212013