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American Journal of Pharmacy and Health Research

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New UV-Spectrophotometric Method Development and Validation for the Assay of Cilostazol in Pure and Formulations

Published in August 2015 Issue 8 (Vol. 3, Issue 8, 2015)

New UV-Spectrophotometric Method Development and Validation for the Assay of Cilostazol in Pure and Formulations - Issue cover

Abstract

A simple, new UV-spectrophotometric method has been developed and validated for the assay of cilostazol in pure and formulations based on measurement of absorption at maximum wavelength of 257.40nm. The developed method exhibited linearity in the range 2.5-15μg/ml with precision is exemplified by relative standard deviation of 0.86% for cilostazol. The percentage mean recovery of cilostazol was found to be in the range of 98.39‐99.34% during accuracy studies respectively. The proposed method is further validated statistically in accordance with ICH norms and the validation results allowed the feasibility of the proposed method in the analysis of cilostazol in pure and its formulations.

Authors (2)

Suresh T

Department of Chemistry, RVR &...

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Rambabu K

Department of Chemistry, RVR &...

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Article Information

AJPHR308009

AJPHR-30-000009

2015-08-01

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T & K (2015). New UV-Spectrophotometric Method Development and Validation for the Assay of Cilostazol in Pure and Formulations. American Journal of Pharmacy and Health Research, 3(8), xx-xx. https://ajphr.com/articles/AJPHR308009

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