Phytochemical Investigation and Pharmacological Screening of Mimusops elengi Linn. bark for its in-vitro anti arthritic and wound healing activity

Mimusops elengi is the most traditionally used medicinal plant that belongs to family Sapotaceae, commonly known as Spanish cherry is native to the Western Ghat region of the peninsular India. By looking the high traditional use of the plant , the present investigation was undertaken which deals with pharmacognostic (moisture content, ash value, extractive value) and phytochemical screening of Mimusops elengi bark .The main aim of this study was to evaluate the invitro anti- arthritic (Protein denaturation and Heat induced haemolysis) and wound healing (Chick chorioallantoic membrane model) activity for methanolic extract of bark. The maximum membrane stabilization of methanolic extract of M. elengi L bark was found to be 80.31% at a dose of 250mcg/ ml and that of inhibition of protein denaturation was found to be 82.37% at a dose of 250mcg/ml with regards to standard (Diclofenac sodium) in the anti-arthritic activity. The alcoholic extract was also capable of promoting angiogenesis in chick eggs which is an indication of its wound healing activity. From the results it can be concluded that M. elengi extract shows good in vitro anti-arthritic and wound healing activities.