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9409046853
e-ISSN: 2321-3647
American Journal of Pharmacy and Health Research

American Journal of Pharmacy and Health Research

Dr. Ankita Ramteke

Author Profile
Department of Conservative Dentistry and Endodontics Ranjeet Deshmukh Dental College (VSPM Dental College), Nagpur, India
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Publications by Dr. Ankita Ramteke

1 publication found • Active 2026–2026

2026

1 publication

COMPARATIVE EVALUATION OF INJECTION PAIN DURING ADMINISTRATION OF LOCAL ANAESTHESIA AFTER TOPICAL ANAESTHETIC GEL VERSUS CRYOTHERAPY APPLICATION: A RANDOMISED CONTROLLED TRIAL

with Dr. Sunayana Bidave, Dr. Pratima Shenoi, Dr. Chetana Makade, Dr. Gautam Badole
8/1/2026
pp. 16-23

Background: The insertion of local anesthetic solution remains one of the most dreaded events during dental treatment, and discomfort from needle penetration is a recognised source of dental anxiety and treatment avoidance. Topical anesthetic gels and pre-injection cooling (cryotherapy) have both been proposed to reduce this discomfort, yet direct comparisons in adult endodontic patients are limited. Objective: To compare pain perception during administration of local anesthesia following a 2% lignocaine topical gel versus a standardized ice-stick cryotherapy protocol. Materials and Methods: In this two-arm crossover randomized controlled trial, patients aged 18–60 years requiring endodontic treatment in at least two teeth received both protocols at separate sites: 2% lignocaine gel (Group A) for 1 minute and a customized ice stick measuring 5 mm × 10 mm (Group B) for 15 seconds before injection. Injection pain was self-rated on a 10 cm visual analogue scale (VAS), and scores were compared using the Mann–Whitney U test at a 5% level of significance. Results: The mean VAS score was 3.65 ± 1.00 in Group A and 2.53 ± 0.94 in Group B, a statistically significant difference (z = −2.888, p = 0.004) indicating lower injection pain with cryotherapy. Conclusion: Pre-injection cryotherapy using a standardized ice stick produced significantly less injection pain than 2% lignocaine topical gel. It offers a simple, inexpensive and non-pharmacological chairside adjunct that can be readily incorporated into routine endodontic practice.

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