e-ISSN: 2321-3647
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American Journal of Pharmacy and Health Research

N.Murali Krishna

Author Profile
Department of Basic humanities, Velagapudi Ramakrishna Siddhartha Engineering College
1
Publications
1
Years Active
1
Collaborators
40
Citations

Publications by N.Murali Krishna

1 publication found • Active 2014-2014

2014

1 publication

A New Validated Stability-Indicating RP-HPLC Assay Method for Pentoxifylline In Bulk Drug

with S.V.M.Vardhan2 C.Rambabu
2/1/2014

An isocratic reversed phase stability-indicating reverse phase high-performance liquid chromatographic (HPLC) assay method have been developed and validated for the determination of pentoxifylline in bulk drugs. Separation of pentoxifylline from the degradation products was carried out using an Inertsil ODS C18 (250cm x 4.6)mm,5u column  with  mobile phase consisting a mixture of  acetonitrile  and  KH2PO4 buffer (pH 4.0) in the ratio of (60:40v/v). The detection was carried out at wavelength 275nm. The developed method was validated with respect to linearity, accuracy (recovery), precision, system suitability, selectivity prove the stability indicating ability of the method.

Author Statistics
Total Publications:1
Years Active:1
First Publication:2014
Latest Publication:2014
Collaborators:1
Citations:40