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📢 Latest Update: Call for Papers – Special Issue on Pharmacy and Health Research (April 2026 Submission Deadline)

📢 Latest Update: Call for Papers – Special Issue on Pharmacy and Health Research (April 2026 Submission Deadline)

Volume 13, Issue 9 - 2025 (September 2025 Issue 09)

Volume 13 Issue 9 Cover

Issue Details:

Volume 13 Issue 9
Published:Invalid Date

Editorial: September 2025 Issue 09

Welcome to the 2025 issue of American Journal of Pharmacy and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Hemangi J Patel
Editor-in-Chief
American Journal of Pharmacy and Health Research

Articles in This Issue

Showing 3 of 3 articles
Research PaperID: AJPHR1309001

Idiopathic Thrombocytopenic Purpura : A Review and Case Report

Divya Amaravadi, Bukka Dheeraj Kumar, Anche Janani

ABSTRACTImmune thrombocytopenia (ITP) is a diverse condition in which managing and predicting patient responses to therapy poses a problem. It can develop in healthy people, including kids and young adults, after a viral infection and significantly impair a patient's quality of life. Thrombopoietin receptor agonists (TPO-RAs), spleen tyrosine kinase (Syk) inhibitors, or immunological suppression (corticosteroids and intravenous immunoglobulins) are the mainstays of ITP treatment. This article provides a quick overview of the occurrence, aetiology, classification, and several therapy approaches based on recent research. We also present a case report on ITP and summarize the key points in the diagnosis and management of it. In order to improve the disease prognosis and lower the incidence or frequency of refractoriness, a deeper understanding of ITP is needed in order to offer patients with individualized therapy alternatives. Keywords: Immune thrombocytopenia, Thrombopoietin receptor agonists, corticosteroids, Syk inhibitors, immunoglobulins.

Immune thrombocytopeniaThrombopoietin receptor agonistscorticosteroidsSyk inhibitorsimmunoglobulins.
111,830 views
33,519 downloads
DOI:
10.5281/zenodo.17875502

Contributors:

 Divya Amaravadi
,
 Bukka Dheeraj Kumar
,
 Anche Janani
Research PaperID: AJPHR1309002

Evaluation Of Synergistic Amalgamation of Medicinal Herbs In the Treatment of Urolithiasis

Kakaraparthy Ravi Shankar*, Kodi Gnaneswari,, Siriki Thirumala Devi, Bhimireddy Niharika. 1.Department of Pharmacology, Aditya College of Pharmacy, Surampalem, 533437, Andhra Pradesh, India.

ABSTRACTUrolithiasis commonly referred to as kidney stones occurs due to the intricate connection of dietary practices, environmental factors, genetics and urinary tract anatomy which varies substantially with prevalence rising globally as a consequence of lifestyle changes. Ayurvedic medicinal herbs offer a natural and holistic approach in managing urolithiasis, minimizing recurrence and side effects, compared to allopathic treatments, which often carry risks like gastrointestinal disturbances and renal toxicity. In this regard a unique blend of three medicinal herbs- Aerva lanata, Tribulus terrestris, and Eugenia jambolana are combined to improve the therapeutic effectiveness which showed amalgamation revealing phytoconstituents that had stone dissolving properties confirmed through FTIR studies.This herbal blend in liquid form is a novel approach to treat calculi that occur in the urinary tract with genuine attempt being made to create a novel liquid formulation which achieved a synergistic effect that showed the removal of calculi from the urinary system yet retaining safety. The synergistic effect of liquid formulation was studied by taking male albino rats and administrating 0.75 % v/v of Ethylene glycol mixed with purified water to induce urolithiasis. The administration of the liquid formulation was given from day 15-28 and the analysis of biochemical parameters like oxalate, calcium and phosphate from urine samples and calcium, uric acid and creatinine from serum were analyzed. The study revealed the anti-urolithiatic activity of the liquid formulation through inhibition of biochemical parameters which supports treatment of urolithiasis. Keywords: Urolithiasis, Aerva lanata, Tribulus terrestris, Eugenia jambolana, FTIR spectrum, Phytoconstituents.

UrolithiasisAerva lanataTribulus terrestrisEugenia jambolanaFTIR spectrumPhytoconstituents.
111,577 views
33,629 downloads
DOI:
10.5281/zenodo.17875536

Contributors:

 Kakaraparthy Ravi Shankar*, Kodi Gnaneswari,, Siriki Thirumala Devi, Bhimireddy Niharika. 1.Department of Pharmacology, Aditya College of Pharmacy, Surampalem, 533437, Andhra Pradesh, India.
Research PaperID: AJPHR1309003

Exploring the Antioxidant and Anxiolytic Biological Activities of Spinacea Oleracea Seed Extract

K. Ravi Shankar, V. Keerthana, S. Amala

ABSTRACTSpinacia oleracea is a green leafy vegetable widely consumed for its nutritional value. The present research work is focused on spinacia oleracea seed extract for evaluation of in vitro antioxidant and in vivo anxiolytic activities. Spinach leaves antioxidant properties are well documented but the bioactive potential of seeds remains unexplored. Hence this research work aims to explore the antioxidant and anxiolytic effects of Spinacia oleracea seed extract using standard in vitro and in vivo methods. The in vitro antioxidant potential of the spinacia oleracea seed extract at dose of 50,100,300 and 500µg/ml were assayed using hydroxyl radical scavenging, nitric oxide, and DPPH radical scavenging assay and results are compared with standard reference drug Gallic acid at concentration 2.5µg/ml. In behavioral studies, spinacia oleracea seed extract at dose of 75mg/kg and 150mg/kg was tested on albino mice subjected to standard behavioral paradigms such as elevated plus maze, open field test, hole board test, and y-maze. The results of these effects were compared to standard anxiolytic drug diazepam. The results obtained were encouraging and indicated significant antioxidant and anxiolytic effect. The FTIR studies revealed that the seed extract was rich in phenolic compounds known for its antioxidant property.Keywords: Spinacia oleracea; antioxidant; DPPH; anxiolytic; elevated plus maze; FTIR  

Spinacia oleraceaantioxidantDPPHanxiolyticelevated plus mazeFTIR
111,847 views
33,492 downloads
DOI:
10.5281/zenodo.17875566

Contributors:

 K. Ravi Shankar
,
 V. Keerthana
,
 S. Amala

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