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American Journal of Pharmacy and Health Research

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📢 Latest Update: Call for Papers – Special Issue on Pharmacy and Health Research (April 2026 Submission Deadline)

📢 Latest Update: Call for Papers – Special Issue on Pharmacy and Health Research (April 2026 Submission Deadline)

Volume 1, Issue 3 - 2013 (June 2013 Issue 3)

Volume 1 Issue 3 Cover

Issue Details:

Volume 1 Issue 3
Published:Invalid Date

Editorial: June 2013 Issue 3

Welcome to the 2013 issue of American Journal of Pharmacy and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Hemangi J Patel
Editor-in-Chief
American Journal of Pharmacy and Health Research

Articles in This Issue

Showing 4 of 4 articles
Research PaperID: AJPHR13001

Preformulation Studies of Pharmaceutical New Drug Molecule & Products: An Overview.

Kailash Vilegave, Gali Vidyasagar, Pratibha Chandankar

Every drug has intrinsic chemical and physical properties which has been consider before development of pharmaceutical formulation. This property provides the framework for drug’s combination with pharmaceutical ingredients in the fabrication of dosage form. Objective of Preformulation study is to develop the elegant (stable, effective, and safe ) dosage form by establishing kinetic rate profile, compatibility with the other ingredients & establish Physico-Chemical parameter of new drug substance.  Among these properties, drug solubility, partition coefficient, dissolution rate, polymorphic forms and stability are plays important role in Preformulation study. Polymorphism having crystal and amorphous forms shows different chemical physical and therapeutic description of the drug molecule. So the for study of crystal properties some techniques are mentioned in this article. And also stability of drug and product how they affected and prevention is mentioned. Preformulation study is a step in time saves nine that is disastrous effect after formulation is prevented in advance. 

PreformulationStability testingPhysic-Chemical propertiesPolymorphism.
2,640 views
785 downloads

Contributors:

 Kailash Vilegave
,
 Gali Vidyasagar
,
 Pratibha Chandankar
Research PaperID: AJPHR13002

Tramadol: An Analgesic to Treat Chronic Pain

Gaurav Solanki, Renu Solanki

Pain is defined by the International Association for the Study of Pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Pain has now been equated to a fifth vital sign highlighting the significance of pain management in patient care. Tramadol is a centrally acting analgesic which is structurally related to codeine and morphine. It is effectively used to treat moderate to severe acute and chronic pain in diverse conditions. Tramadol is placed on the second step of WHO analgesic ladder and in contrast to traditional opioids, exerts its analgesic activity, a dual mechanism of action inhibiting transmission as well as perception of pain. Tramadol is more suitable than NSAID’s and coxib’s for patient with GI, renal and cardiovascular problems. Combined with low dependence/abuse potential, it has proven to be of significant advantage over other agents especially in the elderly.

TramadolAnalgesicPainCyclo-oxygenaseAdverse Effectsetc.
2,768 views
723 downloads

Contributors:

 Gaurav Solanki
,
 Renu Solanki
Research PaperID: AJPHR13003

Azadirachta Indica and Aloe Vera Leaves Extracts Enhances Excision Wound Healing Activity

Shiv Kumar Purohit, Ratan Lal Soni, Renu Solanki

Wounds are major responsible for physical disabilities. Wound disease spread by the invasion of bacteria inside the body through skin. Most of pathogenic microorganisms responsible for wound include Staphylococcus aureus, Streptococcus pyogenes, Enterococci, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. Bacterial infections on skin are the common ailment for generation of other diseases in the body. Wound infections represent the invasion of tissues by number of species of microorganisms. These infections disturb the immune system of body and cause delayed wound healing. Aloe vera leaves pulp is used for medicinal purposes, including treatment of constipation, asthma, diabetes, peptic ulcer, inflammation, wound healing, heart burn, heat stroke etc. While Azadirachta indica is useful in tiredness, cough, fever, loss of appetite, worm infestation. It heals wound, heat-rash, boils, jaundice, leprosy, skin disorders, eye disorders, stomach ulcers, chicken pox, excessive thirst, diabetes and insect poisons. It act as anti-leprotic, antimalarial, anti-hemorrhoidal and anthelmintic agent. The present study was undertaken on evaluation of combinational effect of ethanolic extract of Aloe vera leaves pulp and Azadirachta indica leaves for wound healing activity through topical route on excision wound model. The activity was compared with standard drug Povidone Iodine ointment(5% w/w). Combinational effect of both extract was showed faster wound healing effect than standard drug Povidone Iodine ointment on excision wound model.

Aloe veraAzadirachta indicapovidone iodine ointmentwound healing activityexcision wound model.
2,695 views
874 downloads

Contributors:

 Shiv Kumar Purohit
,
 Ratan Lal Soni
,
 Renu Solanki
Research PaperID: AJPHR13004

Importance of Fluoride in Controlling Fluorosis and Dental Caries

Gaurav Solanki

The use of fluorides for oral health has always involved a balance between the protective benefit against dental caries and the risk of developing fluorosis. The link between fluoride and dental health was established to determining the causes of dental fluorosis or enamel mottling. Fluorosis in Indian children was highly prevalent in the early 1990s. Policy were introduced to control fluoride exposure and to reduce the prevalence of fluorosis. The study aimed of describing the prevalence, severity and risk factors for fluorosis, and to describe the trend of fluorosis among Indian children. The study also aimed of exploring the effect of the change in fluoride exposure on dental fluorosis and caries. Establishing an appropriate use of fluoride toothpaste could be successful in reducing fluorosis without a significant increase in caries experience.

FluorideFluorosisdental cariesDMFTDMFS etc.
2,932 views
879 downloads

Contributors:

 Gaurav Solanki

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