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📢 Latest Update: Call for Papers – Special Issue on Pharmacy and Health Research (April 2026 Submission Deadline)

📢 Latest Update: Call for Papers – Special Issue on Pharmacy and Health Research (April 2026 Submission Deadline)

Volume 8, Issue 4 - 2020 (April 2020 Issue 4)

Volume 8 Issue 4 Cover

Issue Details:

Volume 8 Issue 4
Published:Invalid Date

Editorial: April 2020 Issue 4

Welcome to the 2020 issue of American Journal of Pharmacy and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Hemangi J Patel
Editor-in-Chief
American Journal of Pharmacy and Health Research

Articles in This Issue

Showing 4 of 4 articles
Research PaperID: AJPHR804001

Formulation and Evaluation of Polyherbal Anti-Tussive Syrup

RB. Rajmane, Adnan A. Q. Shaikh, Amol A. Joshi, Azmina TI. Qadri Sayyed

ABSTRACTNow a days the synthetic and novel drugs are the major source of curing any type of disease, although these chemically synthesized drugs are harmful hazardous and shows toxic effect on the human body, this research formulation is a Polyherbal product (expectorant) which is useful and effective to treat the acute as well as chronic cough mainly chronic cough in patients of all ages. The prolonged chronic cough which last for several months or even years (in some patients) so to treat this “polyherbal anti-tussive syrup” is best mode, this syrup consist of some prominent and effective naturally occurring drugs or medicinal plants like, cinnamon, clove, black paper, Tulsi , honey (as base), and menthol (as cooling agent expectorants). This particulate combination of drugs is very effective for the treatment of cough, although this syrup can also be used for the treatment of the common cold respiratory disorders or nasal problems.        Keywords: Anti-tussive, Medicinal Plants, Polyherbal Formulation, Expectorants, Cough Syrup

Anti-tussiveMedicinal PlantsPolyherbal FormulationExpectorantsCough Syrup
95,453 views
28,721 downloads
DOI:
10.46624/ajphr.2020.v8.i4.001

Contributors:

 RB. Rajmane
,
 Adnan A. Q. Shaikh
,
 Amol A. Joshi
,
 Azmina TI. Qadri Sayyed
Research PaperID: AJPHR804002

Palladium used As A Catalyst: A Review

Bilal A Bhat, Wasseem Akbar Khanday

ABSTRACTIn this review, the most important Pd-catalyzed C-C cross-coupling named reactions have been presented and discussed. It has been proposed that in Pd-catalysed reactions, the Pd decreases the activation energy or reacting species by simply stabilizing the transition state as it is an unstable and short-lived. The catalyst may get coordinated to one or more of the reactants and remains coordinated throughout the transition state of the catalytic process. During this process, the dissociation of the product either regenerates the Pd directly or generates a species that will be converted into the Pd. This is a typical in enzyme–catalyzed processes occurs in organometallic chemistry.  Keywords: Cross-coupling, Catalytic, enzyme, organometallic, short-lived.

Cross-couplingCatalyticenzymeorganometallicshort-lived.
95,432 views
28,646 downloads
DOI:
10.46624/ajphr.2020.v8.i4.002

Contributors:

 Bilal A Bhat
,
 Wasseem Akbar Khanday
Research PaperID: AJPHR804003

Formulation and In-Vitro Evaluation of Gastro Retentive Floating Drug Delivery System of Losartan Potassium.

K.S. Srilatha, Hemanth.S, Beulah Milton, Snehalatha

ABSTRACTThe objective of the study was to formulate and evaluate gastro retentive floating drug delivery tablets of Losartan potassium. It is an orally active non-peptide angiotensin -II receptor antagonist, used in the treatment of hypertension due to mainly blockade of AT1 receptors. The main reason for low therapeutic effectiveness of Losartan potassium is its narrow therapeutic index, poor bioavailability (25-35%), and short biological half life (1.5-2h). Conventional tablets should be administered 3-4 times to maintain plasma drug concentration. So, to increase therapeutic efficacy, reduce frequency of administration sustained release floating matrix tablets of Losartan potassium were prepared. Present study demonstrates the formulation of sustained release floating matrix tablets of Losartan potassium with various grades of hydroxyl propyl methylcellulose to restrict the drug release preferably in upper part of intestine and to improve its bioavailability and to provide constant drug plasma levels thereby improving the patient compliance. Losartan potassium showed maximum absorbance at 256 nm  so absorbance was measured at the same wavelength and found to obey Beer lamberts law in the concentration range of 10-40 mcg/ml. In the pre formulation study of IR spectra of pure drug with the different polymers showed no interaction, Differential scanning calorimetry experiments were carried out to find out the presence of any interaction among drug and the excipients. Pure drug and individual polymers were subjected to the study and no interactions were observed  .12 formulation of sustained release of Losartan potassium were prepared and they were examined for physical properties and appearance like hardness, thickness, weight variation, thickness, hardness, friability uniformity of drug content  floating lag time  floating duration time and in-vitro drug release studies . I n the study all the powder blends showed good flow ability angle of repose below 25.98±0.07°

Losartan PotassiumGastroretentive dosage forms and HPMC K4M.
95,702 views
28,814 downloads
DOI:
10.46624/ajphr.2020.v8.i4.003

Contributors:

 K.S. Srilatha
,
 Hemanth.S
,
 Beulah Milton
,
 Snehalatha
Research PaperID: AJPHR804004

Efficacy of Unani combo therapy (Hab-e-Surfa and Sharbat-e-Unab) in the management of Upper respiratory troubles

Irfat Ara, Basharat Bukhari, Nighat Ara

ABSTRACTTo determine the efficacy and tolerability of Unani drug preparations Hab-e-Surfa and Sharbat-e- Unab, we conducted the open labeled, non-comparative clinical trial focused on the patients of either sex in the age group between 14 to 60 years with upper respiratory disorders at Regional Research Institute of Unani medicine, University of Kashmir Srinagar from September 2012-September 2015 irrespective of socio economic status. After baseline assessment, a total number of 60 patients with upper respiratory tract disorders were treated with Hab-e-Surfa with the dose of 2 Tabs (Hab) twice a day and Sharbat-e- Unab 2 tsf twice a day for one week. Clinical assessment of disease were assessed at baseline and after treatment. The pre and post treatment score was compared statistically and recorded. From the result it was observed that Hab-e-Surfa and Sharbat-e- Unab significantly reduced all the signs and symptoms of upper respiratory tract troubles after one week treatment.  No adverse effect has been noticed during the study period. Hence it is concluded that Hab-e-Surfa and Sharbat-e-Unab acts as expectorant, lubricant ,concoctive, coolant, sedative, febrifuge, demulcent and is a promising Unani herbal preparation which is effective and safe. Keywords:  Sual, Clinical trial, Unani Medicine, Unab, Kashmir.

SualClinical trialUnani MedicineUnabKashmir.
95,648 views
28,784 downloads
DOI:
10.46624/ajphr.2020.v8.i4.004

Contributors:

 Irfat Ara
,
 Basharat Bukhari
,
 Nighat Ara

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