Standardization of Siddha Polyherbal Formulation Vaeppampoovathy Mathirai

Standardization and quality control are essential analytical tools to guarantee the correct identifications of drugs. Adulteration and misidentification of herbal drug can cause dreadful health problems to the public and legal headaches for the pharmaceutical industry. The VPM was prepared according to the Siddha classical literature to treat the anti-dyslipidemic activity. The present study was carried out with specific aim to establish standards for Vaeppampoovathy Mathirai based on organoleptic characters, physico-chemical properties (The total -ash value 9.5%, Acid insoluble ash 1.7%, Water soluble ash 2.8% and the loss on drying at 1050 c was found to be 0.043%), phytochemical analysis showed the presence of rich source of alkaloids, carbohydrates, saponins, tannins, phenols, phytosterol, diterpenes, flavanoids, proteins& aminoacids. SEM analysis showed that VPM was arranged in agglomerates of size of micro particles. EDAX analysis showed the presence of minerals like carbon, oxygen, magnesium, aluminum, silica, sulphur, chloride, potassium, calcium. FTIR showed the peak values which are the fuctional groups present. The sophisticated analysis of instruments were also an essential criteria in studying the surface morphology, topography and the chemical bonds present in them which indirectly correlates with the activity and also an important factor in the standardization of the drugs.