Incidence of Breast Cancer and ABO Blood group: A Hospital Based Study

Blood group antigens being the major antigen in humans are present on the surface of red blood cells and various epithelial cells. Since the majority of human cancer cases are derived from epithelial cells, changes in blood group antigens are an important aspect of cancer.  Thus the present work is designed to study ABO blood group and incidence of breast cancer in patients of Mahavir Cancer Institute. The study has been carried out on 400 breast cancer patients diagnosed and treated at Mahavir Cancer Institute and Research Centre and control blood samples of 200 healthy people were taken randomly and were classified according to their ABO blood group. The blood group frequencies were compared using Chi- square test. In control group of women 28 percent having blood group A. while 37.5 percent has blood group B. 12.5 percent and 22 percent has blood group AB and O.  In breast cancer 21.2 percent has blood group A. While 35.1 percent, 7.3 percent and 36.4 percent has blood group B, AB and O respectively. Thus it is evident from study that blood group O has more chances to develop breast cancer, while blood group B also has increased incidence of breast cancer. More than two third patients of breast cancer belong from these two groups. While blood group AB and A has less incidence of breast cancer comparatively. It is quite clear from study that blood group O people were more prone to develop breast cancer.