Byadgi P S

Those substances that cause an unnatural increase in the humors but do not expel them out of body are called Viruddha ahara. Hence, they are more antagonistic than nourishing to the tissues. Many of food materials mentioned in this context in treatises cannot be identified. The interaction is more important. There is concept of drug-drug or food-drug interaction in modern medicine also. In today’s era most of these incompatibilities can be explained chemically and ultimately, leading to ama formation in body. Amavata develops due to conglomeration of ama and vata. According to Ayurveda, ama plays an important role in the pathogenesis of this disease, which is formed mainly due to decrease in digestive power. Acharya Madhava has described various types of nidana responsible for the development of Amavata and viruddha ahara is one of them which plays the most crucial point in today’s era. Viruddha ahara causes vitiation in agni causing vitiation in doshas and vice-versa.

Beeja, Beejabhaga & Beejabhagaavayava are the fundamental factors responsible for the genesis of human being. Ayurvedic Acharyas explained the genetic concept to a greater extent and which simulate with the contemporary concept of genetics mentioned in modern science. Vandhya, Putipraja, Varta and Trina putrika are the diseases manifest due to defect in genes(Beeja, Beejabhaga & Beejabhagaavayava). Phenotypic sex determination begins with genetic sex and which determines phenotypic sex. The nature of gonad present determines the differentiation/regression of the internal ducts (ie, müllerian and wolffian ducts) and ultimately determines the phenotypic sex. Gender identity is determined by the phenotypic appearance of the individual and it is also determined by the brain's prenatal and postnatal development as influenced by the environment.  Any defect in Beeja, Beejabhaga & Beejabhagaavayava causes genetic abnormalities. A diet, behaviours, psychological factors, injuries and iatrogenic factor causes abnormalities in Shukra. Vandhya, klaibya, putipraja, varta, shanda, dwireta etc. are the diseases develop due to shukradushti. It may be  due to Chromosomal problems, hormone imbalance, illness in the mother, disorders of the immune system, abnormalities in the uterus, and environmental and lifestyle factors such as smoking, alcohol and drug use, and exposure to high levels of radiation are often among the  reasons. Keywords- Beeja, Beejabhaga, Beejabhagaavayava, Vandhya, HUMAN GENOME PROJECT