Essential drugs.

Fixed dose combinations (FDCs) are the combinations of two or more active drugs in a single dose form. It is the current hot topic of deliberations in the pharmaceutical industry, drug regulatory agency, and the pharmaceutical trade. Surprisingly, it is not among the doctors prescribe the medicines or the patients who consume. Basically, from one point of view it increases patient compliance, but from other point of view there are chances of consuming medicines, more than what is required. A relook and rationalization may be required in the use of combination product and this is the basis on which this article has been developed.