Herbal medicine

Main objective of the study was to evaluate the efficacy and safety of a Unani formulation in the management of Marz Akyas Khusyatur Rehm (Polycystic Ovarian Syndrome) and to provide the safe, economic and effective alternative therapy for the patients of Marz Akyas Khusyatur Rehm (Polycystic Ovarian Syndrome). A randomized single blind, placebo controlled trial was carried out on 70 patients was at A&U Tibbia College and Hospital Karol Bagh New Delhi. After obtaining ethical clearance, 70 eligible patients was randomly assigned into test and control groups. Test group was administered with 6 gm of Unani formulation orally in the morning and same dose in the evening for three months while control group was given placebo for the same period of time as that of test drug. Written informed consent was sought from every subject before inclusion in the study. Present study was completed within a period of one year. Response was measured by the assessment of pictorial blood loss of assessment, acne, obesity, Hirsutism staging score (Ferrimans Gallewey Score), Acanthosis Nigrican grading, BMI, Serum LH, Serum FSH, LH/FSH ratio, Serum Testosterone and Serum Prolactin. Patient was called for follow up on every 15th day.  The result was statistically analyzed by applying ‘t’test, χ2 test and one way Annova. Test group showed strongly significant decrease in LH/FSH ratio (p

Herbal medicine is currently in demand not only in developing countries but also in developed countries because of their easy availability, low cost and minimum side effects. Long time traditional use of most of the herbs for therapeutic purposes provides a data regarding their safe clinical usage. Piper longum linn is one among such herbs mentioned in various Unani pharmacopeia’s and is indicated for various ailments of human body. It belongs to family piperacea. In Unani system of medicine it is commonly known as Filfil daraz and from last hundreds of years the drug piper longum linn  been accepted to  be as good therapeutic agent particularly for cough, spasmodic pain, inflammation and flatulence.  on the other hand recent Bioavailability enhancing and antioxidant property  has increased it importance for further clinical research . In the present review it has been tried to give a comprehensive data regarding its ethenobotonical particularly of Unani background and phytopharmacological profile of the drug so that to provide a bird eye view presentation of its historical and modern research aspect. Key words:  Herbal medicine, Filfil daraz, piper longum linn, phytopharmocology