amines.
Explore 1 research publication tagged with this keyword
Publications Tagged with "amines."
1 publication found
2015
1 publicationSchiff Bases of Benzimidazole Analogues: Synthesis, Characterization and Biological Activity
Benzimidazole derivatives play an important role in medicinal field with many biological and pharmacological activities related to it. Extensive biochemical and pharmacological studies have confirmed that the potency of these clinically useful drugs in treatment of microbial infections is encouraging and inspiring for further development of some more potent and significant compounds. A series of benzopyrone substituted benzimidazole derivatives were synthesized by reacting benzopyrone-3-carboxylic acid with o-phenylene diamine. The analogues were synthesized in a good yield. The structural characterizations for derivatives were carried out by IR, 1HNMR and Mass spectral studies. The compounds were subjected for antibacterial screening, among them 4c and 4i showed appreciable activity against all the strains. It can be concluded from the antibacterial study that the derivatives may be proved useful for future development.
