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American Journal of Pharmacy and Health Research

Keyword

amines.

Explore 1 research publication tagged with this keyword

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Publications Tagged with "amines."

1 publication found

2015

1 publication

Schiff Bases of Benzimidazole Analogues: Synthesis, Characterization and Biological Activity

Sukhen Som
2/1/2015

Benzimidazole derivatives play an important role in medicinal field with many biological and pharmacological activities related to it. Extensive biochemical and pharmacological studies have confirmed that the potency of these clinically useful drugs in treatment of microbial infections is encouraging and inspiring for further development of some more potent and significant compounds. A series of benzopyrone substituted benzimidazole derivatives were synthesized by reacting benzopyrone-3-carboxylic acid with o-phenylene diamine. The analogues were synthesized in a good yield. The structural characterizations for derivatives were carried out by IR, 1HNMR and Mass spectral studies. The compounds were subjected for antibacterial screening, among them 4c and 4i showed appreciable activity against all the strains. It can be concluded from the antibacterial study that the derivatives may be proved useful for future development.

Keyword Statistics
Total Publications:1
Years Active:1
Latest Publication:2015
Contributing Authors:1