in vitro release

The real challenge in the development of an oral controlled-release drug delivery system is not just to sustain the drug release but also to prolong the presence of the dosage form within the gastrointestinal tract (GIT) until all the drug is completely released at the desired period of time. Floating drug delivery systems (FDDS) have ability to prolong the gastric residence time after oral administration at proper site and release of drug controlled also useful to achieve desired peak plasma concentration and increase bioavailability. This review specify characteristics as well as evaluation of floating microspheres