A Review: Immediate Release Dosage Forms and Legislative Guidelines

Most popular drug delivery in current days was solid drug delivery system it was more suitable in term of manufacturing and testing.  In solid oral dosage forms different grade of filler, binder, disintegrating agent, sweetener, lubricant, glident are used, which play important role in tablet hardness, disintegration and dissolution. Filler, binder, and disintegrating agent, were found to influence tablet dissolution and disintegration, with the filler and disintegrating agent exerting the most significant influence. Slower dissolution was observed with increasing disintegration time when either the filler or the disintegrating agent was kept constant. Generic formulation cover app 90% of all over market. Lots of regulatory body was developed guidelines for industry to develop and testing prepared genric formulation. Generic formulation same in term of strength, shape, release rate, colour, etc. Lot of generic formulation in market for one molecule with same effect in term which show more significant in term of cost and availability.