Liquisolid Technique : A Novel Approach For Enhancement of Solubility and Bioavailability

ABSTRACTLiquisolid strategy is otherwise called powder solution technology. It is the system which manages the solubility upgrade of inadequately solvent medications. As nowadays there are numerous medications in the market with poor solvency which prompts poor disintegration and bioavailability, so dissolvability is getting to be rate constraining component in the advancement of new medications. To defeat this issue there are numerous systems yet liquisolid strategy is most encouraging procedure which is talked about in this article. Liquisolid is for the most part made out of medication, non volatile solvent, carrier material, coating material, and disintegrant. In liquisolid strategy carrier and coating material which ought to be in the proportion of 20:1 is blended into the non volatile solvent and after that disintegrant is included and last material is packed into tablets. Henceforth, the liquisolid innovation permits the change of fluid frameworks into strong medication conveyance frameworks. Both quick and managed arrival of medication can likewise be accomplished with the assistance of liquisolid procedure. For sustained release of medication hydrophilic polymer like Hydroxy Propyl Methyl Cellulose can be the best choice. The motivation behind this article is to depict about the liquisolid strategy like basics, classification, preformulation examines, characterization, pre compression contemplates, detailing of tablet, post compression thinks about, points of interest, drawbacks, applications.Keywords: Liquisolid, bioavailability, dissolution, sustained release.