Binu Mathew

ABSTRACTIndia has taken stringent preventive measures against COVID-19 to control its spread, safeguard citizens and ensure well-being. Public adherence to preventive measures is influenced by their knowledge and attitude toward COVID-19. This study aims to access the knowledge, attitudes, and practices of the public towards COVID-19. A cross-sectional study was contacted in 50 participants using an online self-reported questionnaire. The demographics, knowledge, attitude, and practice of the participants were investigated, and the scores were calculated. The majority of the study participants were knowledgeable about COVID-19, 100% were aware of the clinical symptoms, and 94% knew that there is no clinically approved treatment. It was also evident 40% had low knowledge about wearing masks to prevent infection. Concerning attitudes, participants showed a positive and optimistic attitude toward COVID-19. 40% concur that the virus can be successfully controlled. But 34% are not convinced that the government will control this pandemic. Good knowledge of COVID-19 translates into good and safe practices, which suggests that the practices of residents are very cautious. Almost 88% of respondents refrained from attending social events, 82% avoided crowded places, and 94% avoided shaking hands. We also found that young adults are likely to have better knowledge and practices, than older adult people. The majority of the participants had good knowledge, positive attitude, and sufficient practice. Our finding suggests that targeted health interventions should be directed to this particular vulnerable population, who may be at increased risk of contracting COVID-19.Keywords: Knowledge; Awareness; Practice; Novel coronavirus; COVID 19

ABSTRACTAntibiotic resistance is a condition where in the antibiotic loses its ability to efficiently control or kill the growth of the bacteria due to which the microorganism  continue to multiply  and grow in spite  of the drug being present in therapeutic levels in the body.  Some resistance have no human control over them. How ever, the current scenario of higher levels of antibiotic resistant bacteria are due to the excessive irrational use or abuse of antibiotics.  Patients who were prescribed with either piperacillin / tazobactum or a broad spectrum cephalosporin are enrolled in the study. Demographic data, co morbidities and antimicrobial exposures were collected from the patients. culture sensitivity of  Piperacillin/tazobactum was conducted in the department of microbiology. Resistance is a worldwide concern, it’s first and foremost problem encountering in antimicrobial therapy. In reality, the extensive use of ? lactam antibiotics in hospitals and communities has created major evolutionary pressures in bacteria to evolve towards resistance. The ? lactamase antibiotics are the largest and currently most widely used antibacterial agents. Therefore, their resistance means a level of antimicrobial activity associated with a high likelihood of therapeutic failure. The present study reveals the effectiveness of piperacillin/tazobactum over the commonly prescribed cephalosporins.Keywords: Antibiotic Resistance, cephalosporins, piperacillin, tazobactum, hepato biliary, ? lactamase