H. Doddayya

ABSTRACTMedication adherence is a crucial component in the treatment of chronic diseases. In the elderly, clinicians are faced with a unique set of problems associated with adherence that they may not have been adequately trained for. The present study was designed to assess the socio-demographic profile, adherence and drug-related problems among elderly. Methods: An observational study involving 30 patients aged over 60 years using at least five prescription drugs and discharged from hospital. The occurrence of adherence and DRP were  assessed by means of an identification tool specifically developed for use by community pharmacists, including a semi structured patient interview and a checklist of common DRP. Results: Out of 30 study subjects, it was observed that majority of the study subjects had drug related problems. High, moderate and low adherence to medication was found. Conclusion: It is evident that there is a great need on the part of health care providers to not only prescribe medications to the patients but also make a conscious effort to address the issue of non-adherence to the prescribed medications and other non-pharmacological measures. Keywords: Morisky, Drug compliance, elderly, habits, medications

ABSTRACTDiabetes mellitus is a metabolic-cum-vascular disorder of numerous etiologies described by constant hyperglycemia with aggravations of sugar, fat and protein digestion coming about deformities in insulin emission, insulin activity or both. This issue is every now and again connected with long haul harm, which can prompt disappointment of organs like eyes, kidney, nerves, heart and veins.. In India, diabetes mellitus is influencing 33% of the grown-up populace. It is basically connected with wellbeing trouble just as high financial weight at individual and populace levels. A forthcoming observational investigation was completed in-patients confessed to general medication division of NMCH&RC determined to have diabetes mellitus endorsed with combination treatment of Metformin + Glimepiride and combination treatment of Metformin + Teneligliptin from September 2019 to February 2020. Information was gathered from case sheets of patients and evaluated for their monetary weight dependent on the expense per tablet for long term. Cost viability proportion for the patients with controlled blood glucose level by utilizing a specific medication was determined and likelihood to lessen the diabetes mellitus was assessed. Among 70 in-patients, 38 patients (54.29%) were males and 32 patients (45.71%) were females. Patients are between the age gathering of 41-60 years were more (48.57%). Majority of the patients were conceded with known history of diabetes mellitus (81.43%). A large portion of the patients were endorsed with combination treatment of Metformin + Glimepiride (81.42%) followed with Metformin + Teneligliptin (18.57%). There was a critical positive connection (i.e., p value= 0.5607) between perseverance examples of patients with drug treatment. Likelihood of patients taking combination treatment of Metformin + Glimepiride was 77.19% trailed by patients with combination treatment of Metformin + Teneligliptin. Combination treatment of Metformin + Glimepiride are ha

ABSTRACTSelection of glucocorticoids along with its dose and duration are the important aspects which should be considered while prescribing to the critically ill hospitalized patients. The purpose of this study was to assess the prescription pattern of glucocorticoids and promote appropriate use of it. A prospective observational study, conducted for a period of six months from September 2019 to February 2020 in Navodaya Medical College, Hospital & Research Centre (NMCH&RC) Raichur. Current study was performed in patients of age 18 or above and either sex who were prescribed with Glucocorticoid. All the new cases with drug prescription were included in the study.  Patients who were below 18, ICU patient, lactating and pregnant women were excluded from the study. All the collected data were analyzed with the help of standard guidelines. In the present study, the prescribing of glucocorticoids is found to be appropriate about 84.40 %. However, to ensure safe, effective and well-balanced therapeutic management with glucocorticoids, both patients and prescribers should be more aware of the appropriate dose, dosage regimen, route of administration, duration of therapy and overall guidelines for glucocorticoids prescribing. Hence the involvement of clinical pharmacists in clinical practice helps to increase proper usage of glucocorticoids and optimum outcome. Our study concludes that standard treatment guidelines should be developed at hospital for prescribing of glucocorticoids taking into consideration the patient specific parameters which will improve therapeutic outcomes. Keywords: Prescribing pattern, glucocorticoids, corticosteroids, appropriateness, inappropriateness.

The aim of the study was to detect, document, assess and report the suspected adverse drug reactions.  A prospective-observational study on adverse drug reactions was conducted in a 1000 bedded multi-specialty hospital. Suspected ADRs were analyzed for causality, severity and preventability using appropriate validated scales. A total of 65 ADRs were identified in 2280 admissions during the study period. Severity of the suspected ADRs assessed using Modified Hartwig and Siegel Scale. The study revealed that 2(1.6%) suspected ADRs were severe, 5(8%) ADRs were moderate and 58(90.4%) ADRs were mild in severity. Causality assessment was done by using WHO and Naranjo scale. The assessment by Naranjo scale showed that 16 (24.8%) ADRs were possibly drug-related, whereas 43(65.6%) were classified as probably and 6(9.6%) ADRs were definitely related to the drug, while the assessment done by using WHO scale revealed that 16(24.8%) ADRs were possibly drug-related,18 (27.2%) ADRs were probably drug-related, whereas 7(9.6%) were classified as certainly related to drug. Nine patients (13.8%) were admitted due to an Adverse. Preventability of suspected ADRs assessed by using Modified Schumock and Thornton scale, revealed that 17(26%) ADRs were definitely preventable while 1 (2%) ADRs were probably preventable and 47(72%)of the drug reactions were not preventable. Intervention was required in all ADRs as it indirectly contributed to affect the patient’s Quality Of Life. Our ability to anticipate and prevent such ADRs can be facilitated by the establishment of standardized approaches and active reporting of suspected ADRs.

Rational drug use in pregnancy requires the benefits and potential risk associated with the use of the drug. The adverse effect of drugs on the fetus varies temporarily with time. The study was conducted in the Navodaya Medical College Hospital & Research Center, Raichur for the period of six months. The case files of patients who were admitted in department of OBG were reviewed. The main objective of study was to assess the medicines prescribed to pregnant women during antenatal care, childbirth and lactation at a teaching care hospital. The total numbers of the patients enrolled in the study were 412 out of that 52.45% were in the range of 21-25 years, 71.31% patients were admitted third trimesters of pregnancy, 51.21% were multi- gravida. Common complaints of patients showed that anemia 23.8% and pregnancy induced hypertension (17.8%). Antibiotics (26.10%) were the most prescribed. In category A the maximum number of drugs prescribed in first trimester (41.83%).The study shows considerable medication use during pregnancy, child birth and lactation. Our study suggested that medicine use during pregnancy and lactation should be monitored regularly by analyzing prescription data.