Tagoore Vijaya Lakshmi

To evaluate the anti-inflammatory and anti-diabetic potential of extracts Clitoria ternate flower (CTF) AND Tribulus terristris seed (TTS) by in-vivo pharmacological models using rats. Ternate flower (CTF) AND Tribulus terristris seed (TTS). Extraction by cold maceration techniques using hydro-alcoholic solvent. Evaluation of chemical constituents by various chemical tests. Acute toxicity studies as per OECD guidelines and calculation of ED 50 Anti-inflammatory activity by Carragenan induced rat paw models. Anti-diabetic activity by Alloxon induced diabetes in rats. Statistical analysis by Students t Test. Extraction by Cold Maceration method. Estimation of Phytochemicals by various chemical tests.(3) Acute Toxicity studies by OECD guidelines and dose selected were 200mg and 400mg/kg(4) Phytoconstituents are mostly presents in the Clitoria terneta flower and photosterols and flavonoids are not present in the Tribulus tertaris seed which are highly present in Clitoria terneta flower.Anti-inflammatory Activity of Clitoria ternata flower and Tribulus terristris seed highly seen in group III and V of CTF AND TFS. Least amount present in group II of 39% in CTF and 45% of group IV in TTS..Anti-diabetic Activity of Clitoria ternata flower and Tribulus terristris seed values are Mean ± SEM of Six Animals. Statistical Significance: a = p < 0.001 and b = p < 0.05 as compared to control From the acute toxicity studies the ED 50 of the extract were fixes as 200 and 400 mg/kg. The anti-inflammatory and anti-diabetic activity of both CTF & TTS were calculated by in-vivo methods using rat models. The 400mg/kg of both Clitoria ternata flower (CTF) and Tribulus terristris seed (TTS) extracts showed potential anti-inflammatory and anti-diabetic activity. Further studies are required for structural elucidation of the active component(s) involved in the anti-hyperglycaemic and anti-inflammatory activity of Tribulus terrestris L. and Clitoria ternate

Dialysis is a process of removing waste products and excess fluids from the body. It is divided majorly into four types. Hemodialysis and peritoneal dialysis are majorly used in majority of cases. The principle involved in the hemodialysis and peritoneal dialysis and advantages and disadvantages are discussed below. Complications induced by the both hemodialysis and peritoneal dialysis also mentioned such as nausea, headache, leg cramps etc. Dietary guidelines for patients who are starting on hemodialysis and peritoneal dialysis.