Vaghela D.B

‘Migraine’ comes from the Greek word, hemicranias, which means pain affecting one side of the head (classical Migraine) may affect the entire head. In Ayurveda Ardhavabhedaka there is severe headache in half portion of the head either left or right. So we can correlate Ardhavabhedaka with Migraine. Migraine (Ardhavabhedaka) is one of the most disabling of neurological disorders. The World Health Organization (WHO) has identified migraine among the world’s top 20 leading causes of disability. A clinical study was conducted on this problem with Brihat Jeevakadya Taila (BJT). It was inferred from the results that it was promising result effect in the treatment of Migraine. Till date there is no data regarding evaluation of BJT. It was aimed to develop the pharmacognostical and phytochemical profile of BJT. The samples were subjected to organoleptic, physicochemical analysis and High Performance Thin Layer Chromatography (HPTLC) examination by optimizing the solvent systems. The pharmacognostical study of ingredients of BJT shows the presence of Prismatic crystal, Stellate trichome, Oil globule, Border Pitted vessels etc. Pharmaceutical analysis showed that the loss on drying value was 0.1493% w/w, Specific gravity 0.9197, Refractive index 1.4780, Iodine value 72.21 and High Performance Thin Layer Chromatography at 254 nm and 366 nm resulted into 8 & 7 spots respectively. These parameters of pharmacognosy and pharmaceutical analysis can become the baseline for future.