antibacterial

ABSTRACTAbies webbiana is an ayurvedic medicinal plant used in various herbal formulations.  Plant commonly known by name Talispatra, is an important component of Talisadi churna. A. webbiana leaves have been reported as antibacterial and antifungal, mast cell stabilizing, anxiolytic, antitumor, anti-inflammatory, anti-tussive, female antifertility, febrifuge, anti-spasmodic properties, central nervous system (CNS) depressant actions and are effective against hyperglycemia. Its leaves are mainly used in ayurvedic preparations used for respiratory disorders. A number of phytoconstituents including Monoterpenes (from essential oil), flavonoids, biflavonoid glycosides, phytosterols, amino acids, saponins, tannins, alkaloids, lipids, triterpenoids, steroids and diterpene glycosides are presnt in plant. The plant morphology resembles very much to T. baccata, an important source of taxanes, Even though the medicinal properties and chemical constituents of selected plants are different, their common name and morphology causes confusion in their identity.Keywords:           

ABSTRACTA series of N-{[2-(substituted methylidene)hydrazinyl](methylsulfanyl)methyl}-2-substituted-1,3-thiazolidine-4-carboxamide derivative were synthesized. The synthesized compounds were characterized by IR, NMR, Mass spectral data. The synthesized compounds were screened for their antifungal and antibacterial activity against pathogenic fungus and bacteria. Compounds TS-2, TS-4 and TS-9 exhibited good antibacterial and antifungal activity against the tested microorganisms, and the  rest of the molecules  shows good to moderate activity. Keywords: substitute thiazolidine, microwave assisted synthesis, minimum inhibitory concentration, antibacterial, antifungal.

The Robinia pseudoacacia (Fabaceae) is one of the medicinal plants, Native to North America, commonly distributed in various regions of Kashmir. The plant is used as an antispasmodium, febrifuge, antioxidant;diuretic, emollient, antitumor etc. The present study was carried out to evaluate the anticancer, antibacterial potentials of Robinia pseudoacacia along with the phytochemical screening of the major constituents of the aforesaid plant. The extracts of the Robinia pseudoacacia were phytochemically screened for the presence of Alkaloids, Flavonoids Saponins, Tannins, and Phenols. However the positive results for the detection of Flavonoids, Tannins and phenols were obtained. Further, the Methanolic extract of the same plant was evaluated for its anti-microbial activities where 100mg/ml of the extract showed between 12-19mm inhibitory zones on the test organism. The aforementioned plant’s ethanolic extract also showed anticancer activity against four cancer cell lines – C6, MFC, T47D and A549 using MTT assay.