prescribing pattern

ABSTRACTDementia is one of the most common disorders among elderly patients, Worldwide 7.7 million new cases of dementia were anticipated each year, implying one new case every 4.1 seconds. The aim of the study is to assess the psychiatric co morbidity and prescribing pattern in a tertiary care hospital in south India. This was an Prospective Observational Study conducted at tertiary care hospital. Prospective data was collected from outpatient and inpatient department. Out of 16 patients the common type of dementia reported was Alzheimer’s disease found in ,56.3% of the cases followed by vascular dementia and the prescribed drugs were Memantine (37.5%) is the prescribed drug for most of the dementia cases followed by donepezil (25%), Memantine + donepezil combination (18.75%), Rivastigmine (12.5%), Memantine + Rivastigmine combination  (6.2%). The common type of dementia reported was Alzheimers and Memantine was the most commonly prescribed drug in mono-therapy and among combination therapy Memantine–donepezil combination was mostly prescribed. Keywords: dementia, prescribing pattern, psychiatric co morbidity

To study the prescribing pattern of proton pump inhibitors at a private tertiary care hospital. This was a descriptive retrospective as well as prospective study carried out using 220 inpatient prescriptions in internal medicine department at a private tertiary care hospital. Out of 220 prescriptions of PPIs 56% were male patients and remaining were female among them 12.27% were alcoholics and 6.36% were smokers. It was highly prescribed in the age group of 26-35 (23.64%). Highly prescribed proton pump inhibitor was Pantoprazole (72%), IV route was used mostly 80.91% and about 53% of IV prescriptions were switched to oral route after patient being stable. Vomiting (34%) and nausea (28%) were the most common symptoms of ulcer presented. Fever (22.63%) was the most common condition under therapy and antibiotics (20.50%) were highly prescribed drugs concurrently with PPIs. Average cost per day of IV PPIs was Rs.54.69/day and of oral PPIs was Rs.7.8/day. Out of 43 drug interactions found 14 interactions were with iron. Widespread prescriptions of PPIs should be taken into consideration as it is irrationally prescribed for prophylaxis with various medications where only NSAIDs induced ulcer and its treatment is approved by FDA.