Prasobh GR

ABSTRACTPost stroke depression (PSD) is a mood disorder in which depression and anhedonia results from stroke. Stroke is a neurological deficit of cerebrovascular cause which persist either beyond 24hrs or is interrupted by death within 24hrs. Depression is a common mental disorder characterized by depressed mood, loss of interest, Feeling of guilt, disturbed sleep, decreased appetite. Development of PSD may result from the mental distress associated with physical disability. There is no reliable and universal treatment for PSD despite its debilitating effects on quality of life in stroke patients. Most of the antidepressant influences the serotoninergic, adrenergic and dopaminergic systems with the aim of accelerating serotonin, dopamine and nor-epinephrine. The different therapeutic approaches to treat PSD include Antidepressants, psychotherapy, surgical therapy, Transcranial magnetic stimulation, acupuncture, music therapy. In this review we are compiling different treatment options available for post stroke depression. Keywords: Post stroke depression, antidepressant, psychotherapy, Transcranial magnetic stimulation, acupuncture, music therapy

ABSTRACTThe third leading cause of death is stroke, mainly occurred in patients with 50 years or more and it is described as a sudden loss of blood flow to the brain that leads to irreversible tissue damage caused by thrombotic, embolic, or hemorrhagic events. While stroke related psychiatric complications have been recognized for over a century, they have never received the same degree of attention as post stroke motor deficits, language difficulties, or intellectual disturbances. Some of these stroke clinical complications, such as depression and whereas anxiety or emotional liability are other complications. Depression after stroke is associated with a lower quality of life and also with a higher risk of dying. After a stroke, approximately one third of patients experience depression. It’s important to correctly test for and diagnosis post stroke depression, as well as determine the seriousness of the disease. PSD is related to a variety of stroke risk factors and it can be fatal if left untreated. There is good evidence that early initiation of antidepressant treatment is associated with a decreased risk of developing and successful prevention of PSD in non depressed stroke patients. PSD requires special care, and consensus on the diagnosis and treatment of PSD should be achieved. Keywords: Antidepressant, depression, Post stroke depression, Stroke

ABSTRACTDementia is one of the most common disorders among elderly patients, Worldwide 7.7 million new cases of dementia were anticipated each year, implying one new case every 4.1 seconds. The aim of the study is to assess the psychiatric co morbidity and prescribing pattern in a tertiary care hospital in south India. This was an Prospective Observational Study conducted at tertiary care hospital. Prospective data was collected from outpatient and inpatient department. Out of 16 patients the common type of dementia reported was Alzheimer’s disease found in ,56.3% of the cases followed by vascular dementia and the prescribed drugs were Memantine (37.5%) is the prescribed drug for most of the dementia cases followed by donepezil (25%), Memantine + donepezil combination (18.75%), Rivastigmine (12.5%), Memantine + Rivastigmine combination  (6.2%). The common type of dementia reported was Alzheimers and Memantine was the most commonly prescribed drug in mono-therapy and among combination therapy Memantine–donepezil combination was mostly prescribed. Keywords: dementia, prescribing pattern, psychiatric co morbidity