A Review of Tablet in Tablet Vitamin D3 Formulation Techniques
P. Inigo*, R.Ramprasad1, S.R.Senthilkumar1, N. Venkateshan2
Department of Pharmacy, Arulmigu Kalasaligam
College of Pharmacy
The studies is to review formulated core tablets (tablet in tablet) and difficulty in the formulation and evaluation. Numerous techniques are used overcome the problem of stability. The tablet coating have number of advantages like masking odor, taste, color of the drug, providing physical and chemical protection to drug, Protecting drug from the gastric environment. Most of the tablets are instable in gastro industrial tract. Coated, encapsulation, capsules instructed tablet, gel coated tablet. Vitamin D3 containing cholecalciferol (made from 7-dehydrocholesterol in the skin). Several forms (vitamins) of vitamin D exist. The two major forms are vitamin D2 or ergocalciferol, and vitamin D3 or cholecalciferol; vitamin D without a subscript refers to either D2 or D3 or both. Vitamin D3 contain natural foods like Fatty fish, like tuna, mackerel, and salmon Foods fortified with vitamin D, like some dairy products, orange juice, soy milk, and cereals, Beef liver, Cheese, Egg yolks. Industrial production encovndred several evaluation error like weight variation, hardness, friability, thickness, solubility, disintegration test. Here dissolution test not necessary because vitD3 was a supplementary USP not recognized. Nutrients do not work alone, and when it comes to taking vitamin D, its important that you take any compound and vitamin D together and not JUST vitamin d alone in large doses as this can lead to what people BELIEVE are vitamin d side effects.
Keywords: Vitamin D3, cholecalciferol , coated tablet