Prevalence of Dementia and Cognitive Impairment after Stroke: An Epidemiological Study
Sandeep Kumar Beemreddy1*, Amulya Reddy Gade1, Venumadhav Neerati1
1.Department of Pharmacy Practice, St. Peter’s Institute of
Pharmaceutical Sciences, Hanamkonda, Warangal-506 001, India
Vascular dementia and cognitive impairment are major problems in stroke which must be diagnosed properly and very less effort is put into management of cognitive decline after stroke. This study is a prospective; questionnaire based observational study conducted for 6 months among stroke patients admitted into in patient setting of a tertiary care teaching hospital done to estimate the prevalence of stroke based on age, sex and educational status and to estimate the prevalence of dementia and cognitive impairment among stroke patients using neuropsychological testing. Data was collected from a total of 181 stroke patients of the age distribution 20 to 85 y with a mean age of 57.68±12.34 y and 75.6% patients were diagnosed with ischemic stroke and 24.3% with hemorrhagic stroke. Majority (76.79%) of patients were from rural population. Diagnostic and Statistical Manual of Mental Disorders-IV, Revised text criteria were used to assess dementia. Mini-mental state examination and short portable mental state questionnaire were used to know the extent of cognitive impairment. Various comorbid conditions like hypertension, diabetes mellitus, coronary artery disease and epilepsy were observed in 69.06% patients. The percentage (45.83%) of people with mild cognitive impairment is high with short portable mental state questionnaire and the percentage (77.69%) of people with moderate dementia is high using mini-mental state examination. 92.81% patients out of 181 were prescribed with neuroprotective drugs. The tools used for screening dementia are not perfect in case of uneducated patients and patients with low education. Current hypotheses and methodologies for the management of post-stroke dementia must be re-evaluated, and new strategies need to be explored.
Dementia, Cognitive impairment, MMSE, SPMSQ