American Journal Of Pharmacy And Health Research

ISSN NO.: 2321-3647
March 2022 Issue 3

Drug Targeting In Neoplastic Disorders

D.Rama Brahma Reddy*, K.Malleswari1, Sudharani V,. Navratha S, Vamsi Krishna

Nalanda institute of pharmaceutical sciences, Kantepudi(v),Sattenapalli(M),Guntur(Dt)


The review on drug targeting in neoplastic disorders emphasizes the various targeting techniques for  effective treatment of the condition. Neoplasm refers to the new growth and its common in any individual, uncontrolled neoplasm results in condition called neoplastic disorder or tumor or cancer. Globally 14.1 million cancer cases were reported in 2012 and the number is expected to reach 24 million by 2035. This review outlines the advances in drug targeting to the neoplastic disorders  keeping in view on the highlights the novel drug delivery systems like liposomes and particulate system like nanoparticles  problems associated with conventional chemotherapy and radiation therapy. It usage in treatment of cancer and effective targeting ways to target the tumor cells without affecting the normal cells. 

Keywords: Chemotherapy, Liposomes, Nanoparticles, Neoplasm.



Herbal Drug Preparation

K. Malleswari*, D. Rama Brahma Reddy1 , A. Vijay1, J. Prakash1, Sk. Ismail1

Nalanda Institute of Pharmaceutical Sciences, Kantepudi(V), Sattenapalli(M), Guntur(Dt)


Herbal medicine has been used for thousands of years. It is estimated that 80% of world population rely on traditional herbal medicine for primary health care. In recent years, herbal remedies have been considered as dietary supplement for disease prevention and as alternative/complementary medicine. A wide variety of herbal medicines are readily available in the market all over the world. With the rising utilization of herbal products, safety and efficacy of herbal medicine have become a public health concern. Adverse health effects associated with herbal products could be attributed to both inherent toxic effects of herbal medicine and toxicities induced by adulterants/contaminants. Increasing evidence, regarding side effects of herbal medicine, has highlighted the demand and necessity of toxicological studies for herbal products. Toxicology constitutes an essential role in the development of herbal medicines. With the advancements of analytical techniques and molecular technology, coupling with the conventional test systems, the ‘-omics-’ technology makes a significant contribution to the predictive and preclinical toxicology of herbal medicine. In this chapter, side effects related to herbal medicine and its adulterants/contaminants are summarized. The recent application of ‘-omics-’ technology for toxicological evaluation of herbal products is also illustrated.

Keywords: Modern herbal medicines, Types of herbs, Methods of preparation, Evaluation of herbal drug products