ABSTRACT

The Pericardium is a membrane like structure which envelops the heart and the proximal great vessels from all around. In normal physiological conditions, there is ~ 10 – 50 ml of pericardial fluid present. But, significant accumulation of pericardial fluid can occur in certain conditions like inflammation or infection of the pericardium and adjacent surrounding structures. This condition can remain asymptomatic for significant time period and incidentally can be found after any imaging investigations for another disease process, or patient can A case of Pericardial Effusion in Patient with Hypertension and CKD Grade-V.present with shock like symptoms due to cardiac tamponade. Here, one point is of significant notification that it is the rate of accumulation of the fluid around pericardium, and not the absolute size of the heart, that primarily determines the symptoms that occur in the pericardial effusion. Meanwhile the clinical suspicion may be introduced by the history of the patient, examination of the patient, electrocardiogram investigation, or chest X-ray. In all these, the echocardiogram is the basic and mainstay to confirm the diagnosis. Options for treatment depends on the etiology and hemodynamics consequences of the heart. This article mainly focuses on the etiology, pathophysiology, investigation, chest X-Ray, CT, and management of the pericardial effusion.

Keywords: Pericardial effusion, Chest X-Ray, Moneybag appearance of Heart, Hypertension, CKD Grade V.

ABSTRACT

Mobile health applications, wearable devices, telehealth platforms, artificial intelligence (AI) applications, and electronic health records have changed healthcare delivery through improving access, efficiency, and participation of patients. Regulatory affairs will have an essential part in assuring the safety, effectiveness, quality, and data security of digital health innovations as they expand and grow fast. By influencing how we classify products, evaluate risk, clinically validate, secure cybersecurity, improve interoperability, and evaluate post-market regulatory pathways, we seek to find a balance between innovation and patient safety.

Keywords: Artificial Intelligence (AI), Mobile Health, Quality Assurance 

ABSTRACT

Dandy-Walker Malformation is characterized by triad of Hypoplasia of vermis, Fourth ventricular cystic dilatation and tentorium cerebelli elevation. It is a rare anomaly of cerebellum which is commonly associated with other chromosomal disorder like Trisomy 13. The ultrasound is very critical and diagnostic imaging modality for diagnosis during antenatal period. We report a case of Dandy-Walker malformation with association of Cleft lip/Cleft palate; posterior spinal defect with myelomeningocele, colpocephaly; and other congenital defects that was diagnosed during a first routine prenatal ultrasound at 21 weeks of gestation.

Keywords: Dandy-Walker Malformation, Antenatal ultrasonography, Posterior fossa, Cyst herniation, Occipital meningoencephalocele, Posterior spinal defect with myelomeningocele, Cleft lip/palate